Kinin B₂ Receptor Mediates Cisplatin-Induced Painful Peripheral Neuropathy by Intracellular Kinase Pathways and TRPA1 Channel Sensitisation

• Autori principali: Gabriela Becker (Autore), Maria Fernanda Pessano Fialho (Autore), Evelyne Silva Brum (Autore), Sara Marchesan Oliveira (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Chemotherapy-induced peripheral neuropathy is a severe clinical problem frequently associated with cisplatin use. Although its pathophysiology is poorly understood, it is known that kinin receptors and the transient receptor potential ankyrin 1 (TRPA1) channel play a significant role in the peripher...