Molecular Targets and Promising Therapeutics of Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) is one of the most heterogeneous diseases in solid tumors and has limited therapeutic options. Due to the lack of appropriate targetable markers, the mainstay therapeutic strategy for patients with TNBC has been chemotherapy for the last several decades. Indeed,...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Published: |
MDPI AG,
2021-09-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_824c806b8b9b48c2be02b9ab0d48ab65 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Won-Ji Ryu |e author |
| 700 | 1 | 0 | |a Joo Hyuk Sohn |e author |
| 245 | 0 | 0 | |a Molecular Targets and Promising Therapeutics of Triple-Negative Breast Cancer |
| 260 | |b MDPI AG, |c 2021-09-01T00:00:00Z. | ||
| 500 | |a 10.3390/ph14101008 | ||
| 500 | |a 1424-8247 | ||
| 520 | |a Triple-negative breast cancer (TNBC) is one of the most heterogeneous diseases in solid tumors and has limited therapeutic options. Due to the lack of appropriate targetable markers, the mainstay therapeutic strategy for patients with TNBC has been chemotherapy for the last several decades. Indeed, TNBC tumors have no expression of estrogen receptor, progesterone receptor, or human epidermal growth factor receptor 2 (HER2); therefore, they do not respond to hormone therapy and HER2-targeted therapy. In this review paper, the molecular heterogeneities, possible therapeutic targets, and recently approved and upcoming drugs for TNBC will be summarized. | ||
| 546 | |a EN | ||
| 690 | |a triple-negative breast cancer | ||
| 690 | |a heterogeneity | ||
| 690 | |a molecular target | ||
| 690 | |a new drugs | ||
| 690 | |a Medicine | ||
| 690 | |a R | ||
| 690 | |a Pharmacy and materia medica | ||
| 690 | |a RS1-441 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Pharmaceuticals, Vol 14, Iss 10, p 1008 (2021) | |
| 787 | 0 | |n https://www.mdpi.com/1424-8247/14/10/1008 | |
| 787 | 0 | |n https://doaj.org/toc/1424-8247 | |
| 856 | 4 | 1 | |u https://doaj.org/article/824c806b8b9b48c2be02b9ab0d48ab65 |z Connect to this object online. |