Advances in nanotechnology-based delivery systems for EGFR tyrosine kinases inhibitors in cancer therapy

• Main Authors: Xiaohan Zhou (Author), Kun Shi (Author), Ying Hao (Author), Chengli Yang (Author), Ruoyu Zha (Author), Cheng Yi (Author), Zhiyong Qian (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oral tyrosine kinase inhibitors (TKIs) against epidermal growth factor receptor (EGFR) family have been introduced into the clinic to treat human malignancies for decades. Despite superior properties of EGFR-TKIs as small molecule targeted drugs, their applications are still restricted due to their...