Concentration Kinetics of Serum MMP-9 and TIMP-1 after Blunt Multiple Injuries in the Early Posttraumatic Period

• Autori principali: M. Brumann (Autore), T. Kusmenkov (Autore), L. Ney (Autore), K.-G. Kanz (Autore), B. A. Leidel (Autore), P. Biberthaler (Autore), W. Mutschler (Autore), V. Bogner (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2012-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Metalloproteinases are secreted in response to a variety of inflammatory mediators and inhibited by tissue inhibitors of matrixmetalloproteinases (TIMPs). Two members of these families, MMP-9 and TIMP-1, were differentially expressed depending on clinical parameters in a previous genomewide mRNA ana...