DUSP22 Ameliorates Endothelial-to-Mesenchymal Transition in HUVECs through Smad2/3 and MAPK Signaling Pathways

• Main Authors: Lu Chen (Author), Hongyu Su (Author), Zekai Tao (Author), Cui Liang (Author), Zhongzhao Liu (Author), Yiming Dong (Author), Peipei Zheng (Author), Yuan Liu (Author)
• Format: Book
• Published: Hindawi-Wiley, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endothelial-to-mesenchymal transition (EndMT) is the process by which endothelial cells lose their endothelial properties and acquire mesenchymal characteristics. Dual-specific protein phosphatase 22 (DUSP22) inactivates various protein kinases and transcription factors by dephosphorylating serine/t...