Lipophilicity determination of β-hydroxy-β-arilalkanoic acids by reversed phase liquid chromatography under high pressure

• Main Authors: Savić Jelena (Author), Dilber Sanda (Author), Crevar-Sakač Milkica (Author), Vladimirov Sote (Author), Brborić Jasmina (Author)
• Format: Book
• Published: Pharmaceutical Association of Serbia, Belgrade, Serbia, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lipophilicity parameters (logP) were determined for thirteen synthesized β-hydroxy-β-arilalkanoic acids using reversed phase high performance liquid chromatography. Anti-inflammatory activity and potential selectivity towards cyclooxygenase-2 inhibition of synthetized compounds was assessed. Station...