Traditional Chinese medicines and Alzheimer's disease

Traditional Chinese medicines have been widely investigated for the treatment of Alzheimer's disease (AD) because none of the current therapies-either the cholinesterase inhibitors or antagonist of N-methyl-d-aspartate receptors-has profound effects on halting the progression of AD. In recent y...

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Main Authors: Tzong-Yuan Wu (Author), Chip-Ping Chen (Author), Tzyy-Rong Jinn (Author)
Format: Book
Published: Elsevier, 2011-06-01T00:00:00Z.
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700 1 0 |a Chip-Ping Chen  |e author 
700 1 0 |a Tzyy-Rong Jinn  |e author 
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500 |a 10.1016/j.tjog.2011.04.004 
520 |a Traditional Chinese medicines have been widely investigated for the treatment of Alzheimer's disease (AD) because none of the current therapies-either the cholinesterase inhibitors or antagonist of N-methyl-d-aspartate receptors-has profound effects on halting the progression of AD. In recent years, scientists have isolated many active compounds from herbs, which can alleviate dementia and neurodegenerative syndrome with fewer side effects than conventional drugs and, thus, are regarded as promising drug candidates for AD therapy. In this review, we summarize the latest research progress on six herbs for AD therapy-Huperzia serrata, Amaryllidaceae family, Ginkgo biloba, Uncaria rhynchophylla, Polygala tenuifolia, and Salvia officinalis-and focus on the analysis of their active components and possible mechanisms of pharmacological actions on AD. 
546 |a EN 
690 |a Acetylcholinesterase 
690 |a Alzheimer's disease 
690 |a Cognitive impairment 
690 |a Dementia 
690 |a Neuroprotection 
690 |a Traditional Chinese medicine 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Taiwanese Journal of Obstetrics & Gynecology, Vol 50, Iss 2, Pp 131-135 (2011) 
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