Development of a Curcumin-Loaded Polymeric Microparticulate Oral Drug Delivery System for Colon Targeting by Quality-by-Design Approach

• Main Authors: Dana Hales (Author), Lucia Ruxandra Tefas (Author), Ioan Tomuță (Author), Cristian Moldovan (Author), Diana Gulei (Author), Raluca Munteanu (Author), Alina Porfire (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to apply the quality-by-design (QbD) approach for the development of colon-targeted curcumin-loaded polymeric microparticles (Col-CUR-MPs). The proportion of the enterosoluble polymer (Eudragit^® FS) in the polymeric matrix, curcumin concentration,...