Defining key questions for clinical practice guidelines: a novel approach for developing clinically relevant questions

Abstract Background There is no standardised protocol for developing clinically relevant guideline questions. We aimed to create such a protocol and to apply it to developing a new guideline. Methods We reviewed international guideline manuals and, through consensus, combined steps for developing cl...

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Main Authors: Samantha Chakraborty (Author), Bianca Brijnath (Author), Jacinta Dermentzis (Author), Danielle Mazza (Author)
Format: Book
Published: BMC, 2020-09-01T00:00:00Z.
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Summary:Abstract Background There is no standardised protocol for developing clinically relevant guideline questions. We aimed to create such a protocol and to apply it to developing a new guideline. Methods We reviewed international guideline manuals and, through consensus, combined steps for developing clinical questions to produce a best-practice protocol that incorporated qualitative research. The protocol was applied to develop clinical questions for a guideline for general practitioners. Results A best-practice protocol incorporating qualitative research was created. Using the protocol, we developed 10 clinical questions that spanned diagnosis, management and follow-up. Conclusions Guideline developers can apply this protocol to develop clinically relevant guideline questions.
Item Description:10.1186/s12961-020-00628-3
1478-4505