Ewing sarcoma of the uterus: A case report

A case is described of Ewing sarcoma of the uterus, an atypical presentation of an already rare cancer.A 55-year-old woman presented with abdominal pain, abnormal uterine bleeding and a uterine mass that measured 11 × 10 × 14.5 cm and demonstrated heterogeneous enhancement with possible areas of cen...

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Main Authors: Zeynep Tek (Author), Anya Laibangyang (Author), Oluwole Odujoko (Author), Bhavna Khandpur (Author), David Doo (Author)
Format: Book
Published: Elsevier, 2024-10-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Zeynep Tek  |e author 
700 1 0 |a Anya Laibangyang  |e author 
700 1 0 |a Oluwole Odujoko  |e author 
700 1 0 |a Bhavna Khandpur  |e author 
700 1 0 |a David Doo  |e author 
245 0 0 |a Ewing sarcoma of the uterus: A case report 
260 |b Elsevier,   |c 2024-10-01T00:00:00Z. 
500 |a 2214-9112 
500 |a 10.1016/j.crwh.2024.e00640 
520 |a A case is described of Ewing sarcoma of the uterus, an atypical presentation of an already rare cancer.A 55-year-old woman presented with abdominal pain, abnormal uterine bleeding and a uterine mass that measured 11 × 10 × 14.5 cm and demonstrated heterogeneous enhancement with possible areas of central necrosis, concerning for sarcoma. She had a complete surgical resection with total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy, bilateral pelvic lymph node dissection, and excision of mesenteric tumor implants. Her final pathology showed primary Ewing sarcoma-primitive neuroectodermal tumor of the uterus with metastatic spread to the peritoneal cavity. She finished 14 cycles of vincristine-doxyrubicin-cyclophosphamide-ifosfamide, etoposide chemotherapy with no evidence of recurrent metastatic disease at 6-month follow-up.Ewing sarcoma is a rare cancer, predominantly seen in adolescents, that typically are of the bone, although in rare instances it can arise from soft tissue; even rarer are presentations in the female genital tract. Even with typical presentations of Ewing sarcoma of the bone, metastatic disease has an overall poor prognosis. The scarcity of cases of metastatic Ewing sarcoma-peripheral neuroendocrine tumors of the uterus makes the condition especially difficult to study. This report describes a case of Ewing sarcoma of the uterus treated by complete surgical resection and aggressive multimodal chemotherapy. 
546 |a EN 
690 |a Ewing sarcoma of the uterus 
690 |a Primary neuroendocrine tumors 
690 |a Rare tumors of the female urogenital tract 
690 |a Surgery 
690 |a RD1-811 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Case Reports in Women's Health, Vol 43, Iss , Pp e00640- (2024) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2214911224000614 
787 0 |n https://doaj.org/toc/2214-9112 
856 4 1 |u https://doaj.org/article/83a27f34aa9d4c98b2ae89d45c27f42c  |z Connect to this object online.