The Neuroprotective Effects of Flavonoid Fisetin against Corticosterone-Induced Cell Death through Modulation of ERK, p38, and PI3K/Akt/FOXO3a-Dependent Pathways in PC12 Cells

• Auteurs principaux: Pei-Rong Chang (Auteur), Je-Wen Liou (Auteur), Pei-Yi Chen (Auteur), Wan-Yun Gao (Auteur), Chia-Ling Wu (Auteur), Ming-Jiuan Wu (Auteur), Jui-Hung Yen (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The overactive hypothalamic-pituitary-adrenal (HPA) axis is believed to trigger the overproduction of corticosterone, leading to neurotoxicity in the brain. Fisetin is a flavonoid commonly found in fruits and vegetables. It has been suggested to possess various biological activities, including antio...