Extraskeletal Ewing sarcoma of the parapharyngeal space with a unique translocation, t(19;22) (q13.4;q12.2)
Extraskeletal Ewing sarcomas of the parapharyngeal space are extremely rare. It has been documented that Ewing sarcomas are morphologically and molecularly indistinguishable regardless of the tissue of origin. Around 85% of Ewing sarcomas are associated with translocation t(11;22)(q24.1;12.2) genera...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2016-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Extraskeletal Ewing sarcomas of the parapharyngeal space are extremely rare. It has been documented that Ewing sarcomas are morphologically and molecularly indistinguishable regardless of the tissue of origin. Around 85% of Ewing sarcomas are associated with translocation t(11;22)(q24.1;12.2) generating the EWSR1-FLI1 fusion oncoprotein. We report a case of an extraskeletal Ewing sarcoma arising in the parapharyngeal space with a unique translocation: t(19; 22) (q13.4;q12.2). To our knowledge this is the first case of an extraskeletal Ewing sarcoma exhibiting this translocation. |
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| Item Description: | 2214-3300 10.1016/j.ehpc.2015.07.003 |