Update on Hedgehog Pathway Inhibitor Therapy for Patients with Basal Cell Naevus Syndrome or High-frequency Basal Cell Carcinoma

• Ngā kaituhi matua: Babette J.A. Verkouteren (Author), Kelly A.E. Sinx (Author), Marie G.H.C. Reinders (Author), Maureen J.B. Aarts (Author), Klara Mosterd (Author)
• Hōputu: Pukapuka
• I whakaputaina: Medical Journals Sweden, 2022-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Some patients with basal cell carcinoma develop a large number of basal cell carcinomas during their lives. The most common underlying genetic disease that causes multiple basal cell carcinomas is basal cell naevus syndrome. Basal cell naevus syndrome is caused by a germline mutation in patched-1 (P...