Bright line or lottery? On significance and value in medical decision making

It is widely acknowledged that using p-value thresholds as the basis for making decision on health care spending is not appropriate. In the context of medical decision making, we argue that patient preferences need to be a stronger factor. Depending on attitudes to risk, patients might prefer a medi...

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Bibliographic Details
Main Authors: Jörg Mahlich (Author), Srirangan Dheban (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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Summary:It is widely acknowledged that using p-value thresholds as the basis for making decision on health care spending is not appropriate. In the context of medical decision making, we argue that patient preferences need to be a stronger factor. Depending on attitudes to risk, patients might prefer a medical treatment that performs on average worse than a comparator but offers a small probability of a large gain such as a cure. However, what has been labeled 'value of hope' is not yet fully reflected in the decision-making process of drug approval and health technology assessment (HTA). Therefore, patient risk preferences should be formally incorporated within the decision-making framework for regulatory and reimbursement decisions.
Item Description:2001-6689
10.1080/20016689.2021.1981574