Conserved statin-mediated activation of the p38-MAPK pathway protects Caenorhabditis elegans from the cholesterol-independent effects of statins

Objective: Statins are a group of medications that reduce cholesterol synthesis by inhibiting the activity of HMG-CoA reductase, a key enzyme in the mevalonate pathway. The clinical use of statins to lower excess cholesterol levels has revolutionized the cardiovascular field and increased the surviv...

Full description

Saved in:
Bibliographic Details
Main Authors: Irina Langier Goncalves (Author), Sharon Tal (Author), Liza Barki-Harrington (Author), Amir Sapir (Author)
Format: Book
Published: Elsevier, 2020-09-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items