Ameliorated in vitro anticancer efficacy of methotrexate d-α-Tocopheryl polyethylene glycol 1000 succinate ester against breast cancer cells
Abstract Background Methotrexate (MTX), a folate anti-metabolite, has been used widely in the treatment of plenty of malignancies. However, the clinical use is limited because of its poor water solubility (BCS class II drug), nonspecific distribution, drug resistance, short circulation half-life, an...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
SpringerOpen,
2019-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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