Disulfiram in glioma: Literature review of drug repurposing

• Hlavní autoři: Shiyu Zhong (Autor), Shengyu Liu (Autor), Xin Shi (Autor), Xudong Zhang (Autor), Kunhang Li (Autor), Guojun Liu (Autor), Lishuai Li (Autor), Shanwei Tao (Autor), Bowen Zheng (Autor), Weichen Sheng (Autor), Ziyin Ye (Autor), Qichen Xing (Autor), Qingqing Zhai (Autor), Lijie Ren (Autor), Ying Wu (Autor), Yijun Bao (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Gliomas are the most common malignant brain tumors. High-grade gliomas, represented by glioblastoma multiforme (GBM), have a poor prognosis and are prone to recurrence. The standard treatment strategy is tumor removal combined with radiotherapy and chemotherapy, such as temozolomide (TMZ). However,...