Disulfiram in glioma: Literature review of drug repurposing

• Главные авторы: Shiyu Zhong (Автор), Shengyu Liu (Автор), Xin Shi (Автор), Xudong Zhang (Автор), Kunhang Li (Автор), Guojun Liu (Автор), Lishuai Li (Автор), Shanwei Tao (Автор), Bowen Zheng (Автор), Weichen Sheng (Автор), Ziyin Ye (Автор), Qichen Xing (Автор), Qingqing Zhai (Автор), Lijie Ren (Автор), Ying Wu (Автор), Yijun Bao (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Предметы: article
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Gliomas are the most common malignant brain tumors. High-grade gliomas, represented by glioblastoma multiforme (GBM), have a poor prognosis and are prone to recurrence. The standard treatment strategy is tumor removal combined with radiotherapy and chemotherapy, such as temozolomide (TMZ). However,...