Diffuse Facial Hyperpigmentation as a Presenting Sign of Lupus Erythematosus: Three Cases and Review of the Literature

Lupus erythematosus (LE) is an autoimmune disorder commonly affecting the skin; cutaneous lesions may indicate systemic involvement, warranting further evaluation. Photosensitivity, which may result in hyperpigmentation, is a well-known feature of the disease. In contrast, the prevalence of primary...

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Huvudupphovsmän: Shir Azrielant (Författare, medförfattare), Eran Ellenbogen (Författare, medförfattare), Alon Peled (Författare, medförfattare), Valentina Zemser-Werner (Författare, medförfattare), Liat Samuelov (Författare, medförfattare), Eli Sprecher (Författare, medförfattare), Mor Pavlovsky (Författare, medförfattare)
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Publicerad: Karger Publishers, 2021-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Shir Azrielant  |e author 
700 1 0 |a Eran Ellenbogen  |e author 
700 1 0 |a Alon Peled  |e author 
700 1 0 |a Valentina Zemser-Werner  |e author 
700 1 0 |a Liat Samuelov  |e author 
700 1 0 |a Eli Sprecher  |e author 
700 1 0 |a Mor Pavlovsky  |e author 
245 0 0 |a Diffuse Facial Hyperpigmentation as a Presenting Sign of Lupus Erythematosus: Three Cases and Review of the Literature 
260 |b Karger Publishers,   |c 2021-06-01T00:00:00Z. 
500 |a 1662-6567 
500 |a 10.1159/000515732 
520 |a Lupus erythematosus (LE) is an autoimmune disorder commonly affecting the skin; cutaneous lesions may indicate systemic involvement, warranting further evaluation. Photosensitivity, which may result in hyperpigmentation, is a well-known feature of the disease. In contrast, the prevalence of primary hyperpigmentation as a presenting sign of LE is not well established. Here, we compare 3 unique cases of diffuse facial hyperpigmentation as the primary manifestation of LE (cutaneous or systemic) and review previously reported cases. Our data highlight the need for considering LE in the differential diagnosis of facial hyperpigmentation and substantiate the importance of this unique lupus variant in early diagnosis and patient evaluation. 
546 |a EN 
690 |a hyperpigmentation 
690 |a lupus erythematosus 
690 |a photosensitivity 
690 |a connective tissue disorders 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Case Reports in Dermatology, Vol 13, Iss 2, Pp 263-270 (2021) 
787 0 |n https://www.karger.com/Article/FullText/515732 
787 0 |n https://doaj.org/toc/1662-6567 
856 4 1 |u https://doaj.org/article/849af5b8cfd3453dbca20b86030072e3  |z Connect to this object online.