Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi.
Chagas disease is a neglected tropical disease and a leading cause of heart failure in Latin America caused by a protozoan called Trypanosoma cruzi. This parasite presents a complex multi-stage life cycle. Anti-Chagas drugs currently available are limited to benznidazole and nifurtimox, both with se...
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Main Authors: | Isabel S Shiratsubaki (Author), Xin Fang (Author), Rodolpho O O Souza (Author), Bernhard O Palsson (Author), Ariel M Silber (Author), Jair L Siqueira-Neto (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2020-10-01T00:00:00Z.
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