Dispersibility and Storage Stability Optimization of High Dose Isoniazid Dry Powder Inhalation Formulations with <span style="font-variant: small-caps">L</span>-Leucine or Trileucine

• المؤلفون الرئيسيون: Imco Sibum (مؤلف), Paul Hagedoorn (مؤلف), Markus P. G. Kluitman (مؤلف), Martijn Kloezen (مؤلف), Henderik W. Frijlink (مؤلف), Floris Grasmeijer (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2019-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Tuberculosis is the leading cause of death from a single infectious pathogen worldwide. Lately, the targeted delivery of antibiotics to the lungs via inhalation has received increasing interest. In a previous article, we reported on the development of a spray-dried dry powder isoniazid formulation c...