Serum levels of TNF-α, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet's disease

Aim: Behçet's disease (BD) is a systemic immuno-inflammatory disorder and the aetiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case-control study is to investigate serum pro-inflammatory cytokine tumour necrosis f...

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Bibliographic Details
Main Authors: Cem Evereklioglu (Author), Hamdi Er (Author), Yusuf Türköz (Author), Mustafa Çekmen (Author)
Format: Book
Published: Hindawi Limited, 2002-01-01T00:00:00Z.
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Summary:Aim: Behçet's disease (BD) is a systemic immuno-inflammatory disorder and the aetiopathogenesis is to be specified. Cytokines play a role in immune response and in many inflammatory diseases. The aim of this case-control study is to investigate serum pro-inflammatory cytokine tumour necrosis factor (TNF)-α, interleukin-1beta (IL-1β), soluble IL-2 receptor (sIL-2R), IL-6, and chemokine IL-8 levels in patients with BD. We also determined the end product of lipid peroxidation (malondialdehyde (MDA)) in BD patients as an index for oxidative stress.
Item Description:0962-9351
1466-1861
10.1080/09629350220131935