Study of the mass balance, biotransformation and safety of [14C]SHR8554, a novel μ-opioid receptor injection, in healthy Chinese subjects
Background: SHR8554 is a novel μ-opioid receptor-biased agonist. It has analgesic effects by selectively activating the G protein-coupled pathway. Additionally, it can weakly activate the ß-arrestin-2 pathway, resulting in a limited number of side effects, such as gastrointestinal inhibition. Previo...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2023-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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