Utility of Metagenomic Next-Generation Sequencing in Infective Endocarditis: A Systematic Review

• Egile Nagusiak: Sara F. Haddad (Egilea), Daniel C. DeSimone (Egilea), Supavit Chesdachai (Egilea), Danielle J. Gerberi (Egilea), Larry M. Baddour (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Blood cultures have been the gold standard for identifying pathogens in infective endocarditis (IE). Blood culture-negative endocarditis (BCNE), however, occurs in 40% or more of IE cases with the bulk of them due to recent antibiotic exposure prior to obtaining blood cultures. Increasingly, molecul...