USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity
Abstract Background High mobility group box 1 (HMGB1) is a damage-associated molecular pattern (DAMP) molecule that plays a central role in innate immunity. HMGB1 acts as a late mediator of inflammation when actively secreted in response to inflammatory stimuli. Several post-translational modificati...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
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BMC,
2022-12-01T00:00:00Z.
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