First-time detection and identification of the Mycobacterium tuberculosis Complex members in extrapulmonary tuberculosis clinical samples in south Tunisia by a single tube tetraplex real-time PCR assay.

• Main Authors: Mariam Siala (Author), Salma Smaoui (Author), Wafa Taktak (Author), Salma Hachicha (Author), Asma Ghorbel (Author), Chema Marouane (Author), Sana Kammoun (Author), Dhikrayet Gamara (Author), Leila Slim (Author), Radhouane Gdoura (Author), Férièle Messadi-Akrout (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tunisia has one of the highest burdens of extrapulmonary tuberculosis (EPTB) among tuberculosis (TB) cases but the contribution of MTBC-mediated human EPTB is unknown. EPTB diagnosis is challenging due to the paucibacillary nature of clinical samples. Therefore, a need of a simplified molecular meth...