Profile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns

Abstract Objective Gestational diabetes mellitus (GDM) is associated with a higher risk of perinatal morbidity and mortality, and its main complication is the occurrence of large for gestational age (LGA) newborns. The present study aims to characterize pregnant women with GDM and to identify factor...

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Main Authors: Maria da Glória Rodrigues Tavares (Author), Érika Sales Lopes (Author), Rosy Anne de Jesus Pereira Araújo Barros (Author), Rossana Santiago de Sousa Azulay (Author), Manuel dos Santos Faria (Author)
Format: Book
Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2019-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Maria da Glória Rodrigues Tavares  |e author 
700 1 0 |a Érika Sales Lopes  |e author 
700 1 0 |a Rosy Anne de Jesus Pereira Araújo Barros  |e author 
700 1 0 |a Rossana Santiago de Sousa Azulay  |e author 
700 1 0 |a Manuel dos Santos Faria  |e author 
245 0 0 |a Profile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns 
260 |b Federação Brasileira das Sociedades de Ginecologia e Obstetrícia,   |c 2019-06-01T00:00:00Z. 
500 |a 0100-7203 
500 |a 10.1055/s-0039-1687860 
520 |a Abstract Objective Gestational diabetes mellitus (GDM) is associated with a higher risk of perinatal morbidity and mortality, and its main complication is the occurrence of large for gestational age (LGA) newborns. The present study aims to characterize pregnant women with GDM and to identify factors associated with the occurrence of LGA newborns in this population. Methods A cross-sectional study was performed based on medical records of women whose prenatal care and delivery were performed at the Maternal and Child Unit of the HospitalUniversitário of theUniversidade Federal doMaranhão, state of Maranhão, Brazil.A total of 116 pregnant women diagnosed with GDMwere included according to the criteria of the International Association of Diabetes and Pregnancy Study Groups (IADPSG). Results The variables associated with LGA newborns after multivariate analysis were: obesity prior to pregnancy (OR = 11.6; 95% CI: 1.40-95.9), previous macrosomia (OR = 34.7; 95% CI: 4.08-295.3), high blood glucose levels in the 3rd trimester (OR = 2,67; 95% CI: 1.01-7.12) and combined change in the oral glucose tolerance test (OGTT) (fasting + postdextrose) (OR = 3.53;95%CI:1.25-14.2) = 1.17-10.6).Otherwise, insufficientweight gain during pregnancy reduced the risk for LGA newborns (OR = 0.04; 95% CI: 0.01-0.32). Conclusion Obesity prior to pregnancy, previous macrosomia, high blood glucose levels in the 3rd trimester, and combined change in the OGTT were independent predictive factors for LGA newborns in pregnant women with GDM. 
546 |a EN 
546 |a PT 
690 |a gestational diabetes mellitus 
690 |a oral glucose tolerance test 
690 |a large for gestational age 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Revista Brasileira de Ginecologia e Obstetrícia, Vol 41, Iss 5, Pp 298-305 (2019) 
787 0 |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032019000500298&tlng=en 
787 0 |n http://www.scielo.br/pdf/rbgo/v41n5/1806-9339-rbgo-41-05-298.pdf 
787 0 |n https://doaj.org/toc/0100-7203 
856 4 1 |u https://doaj.org/article/8583df24512b41dba39f38a35b44c70a  |z Connect to this object online.