High Prevalence of Parvovirus B19 IgG Antibody among Hemophilia Patients in Center for Special Diseases, Shiraz, Iran

Human parvovirus B19, the causative agent of fifth disease in childhood, is non-enveloped DNA virus and resistant to many physicochemical agents. B19 is a potential risk to hemophiliac patients receiving blood products. To determine the prevalence of the corresponding antibody in patients with hemop...

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Bibliographic Details
Main Authors: M Mahmoodian Shooshtari (Author), M Nabi Foroghi (Author), R Hamkar (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2005-03-01T00:00:00Z.
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Summary:Human parvovirus B19, the causative agent of fifth disease in childhood, is non-enveloped DNA virus and resistant to many physicochemical agents. B19 is a potential risk to hemophiliac patients receiving blood products. To determine the prevalence of the corresponding antibody in patients with hemophilia A or B or Von Will brand's disease (VWBD), we tested 180 hemophilia patients aged 1-45 years for anti B19 IgG. This work was descriptive, cross-sectional study. The results were compared with those of 400 age-matched controls, male blood donors and male children (18-45 and 3-17 years of age, respectively). The overall prevalence of B19 IgG in the hemophilia patients was 74% (133/180), and in the controls 56.5% (226/400, P
Item Description:2251-6085
2251-6093