Effects of early- and mid-life stress on DNA methylation of genes associated with subclinical cardiovascular disease and cognitive impairment: a systematic review

• Autori principali: Elena M. Vidrascu (Autore), Alexander C. Bashore (Autore), Timothy D. Howard (Autore), Justin B. Moore (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2019-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Traditional and novel risk factors cannot sufficiently explain the differential susceptibility to cardiovascular disease (CVD). Epigenetics may serve to partially explain this residual disparity, with life course stressors shown to modify methylation of genes implicated in variou...