Drug-like properties of serial phenanthroindolizidine alkaloid compounds: ADMET characteristic prediction and validation

• Main Authors: Hongliang Wang (Author), Jinping Hu (Author), Ming Ji (Author), Rubing Wang (Author), Jing Jin (Author), Jun Ye (Author), Haijing Zhang (Author), Lin Li (Author), Renyun Wang (Author), Yanfang Yang (Author), Yue Gao (Author), Xuejun Xia (Author), Xueqing Xu (Author), Lili Gao (Author), Yuling Liu (Author)
• Format: Book
• Published: Compuscript Ltd, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phenanthroindolizidine alkaloids (PAs) are a series of compounds that have been isolated from traditional herbal medicines and have significant therapeutic potential, such as anti-arthritic, anti-viral, anti-inflammatory, and anti-glioma effects in vitro and in vivo . This study aimed to predict the...