HER2-expressing breast tumors are associated with breast cancer stem-cell phenotype CD44+/CD24-

• Main Authors: Iris Rabinovich (Author), Lúcia de Noronha (Author), Ana Paula M. Sebastião (Author), Rubens S. Lima (Author), Cícero A. Urban (Author), Eduardo Schunemann Jr (Author), Selene Elífio-Esposito (Author), Cleverton C. Spautz (Author), Andréa N. Moreno-Amaral (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT INTRODUCTION: According to the cancer stem-cell theory, tumors originate from a small population of cancer stem cells, which lose the mechanism of self-regulation and begin to differentiate and proliferate indefinitely. The CD44+/CD24- phenotype may be considered a stem-cell marker in breas...