Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of 177Lu‐PSMA‐617 in prostate cancer patients

• Main Authors: Hinke Siebinga (Author), Bastiaan M. Privé (Author), Steffie M. B. Peters (Author), James Nagarajah (Author), Thomas P. C. Dorlo (Author), Alwin D. R. Huitema (Author), Berlinda J. deWit‐van der Veen (Author), Jeroen J. M. A. Hendrikx (Author)
• פורמט: ספר
• יצא לאור: Wiley, 2023-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Studies to evaluate and optimize [177Lu]Lu‐PSMA treatment focus primarily on individual patient data. A population pharmacokinetic (PK) dosimetry model was developed to explore the potential of using imaging data as input for population PK models and to characterize variability in organ and...