A Case-Study of Implementation of Improved Strategies for Prevention of Laboratory-acquired Brucellosis

• Main Authors: Louisa J. Castrodale (Author), Gregory A. Raczniak (Author), Karen M. Rudolph (Author), Lori Chikoyak (Author), Russell S. Cox (Author), Tricia L. Franklin (Author), Rita M. Traxler (Author), Marta Guerra (Author)
• Format: Knjiga
• Izdano: Elsevier, 2015-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Izvleček

Background: In 2012, the Alaska Section of Epidemiology investigated personnel potentially exposed to a Brucella suis isolate as it transited through three laboratories. Methods: We summarize the first implementation of the United States Centers for Disease Control and Prevention 2013 revised recommendations for monitoring such exposures: (1) risk classification; (2) antimicrobial postexposure prophylaxis; (3) serologic monitoring; and (4) symptom surveillance. Results: Over 30 people were assessed for exposure and subsequently monitored for development of illness. No cases of laboratory-associated brucellosis occurred. Changes were made to gaps in laboratory biosafety practices that had been identified in the investigation. Conclusion: Achieving full compliance for the precise schedule of serologic monitoring was challenging and resource intensive for the laboratory performing testing. More refined exposure assessments could inform decision making for follow-up to maximize likelihood of detecting persons at risk while not overtaxing resources.

Opis knjige/članka

2093-7911
10.1016/j.shaw.2015.07.009