The effect of amantadine on an ion channel protein from Chikungunya virus.
Viroporins like influenza A virus M2, hepatitis C virus p7, HIV-1 Vpu and picornavirus 2B associate with host membranes, and create hydrophilic corridors, which are critical for viral entry, replication and egress. The 6K proteins from alphaviruses are conjectured to be viroporins, essential during...
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Public Library of Science (PLoS),
2019-07-01T00:00:00Z.
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