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Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway

Excessive reactive oxygen species (ROS) production leads to oxidative stress in cells, impairing the function of mitochondria and finally inducing cell apoptosis. Considering the essential role of oxidative stress in the pathogenesis of various neurodegenerative diseases and psychiatric disorders, t...

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Bibliographic Details
Main Authors:	Liang Xiong (Author), Hongshan Wu (Author), Ting Zhong (Author), Fang Luo (Author), Qing Li (Author), Mei Li (Author), Yanhua Fan (Author)
Format:	Book
Published:	MDPI AG, 2022-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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