Rapid implementation of a clinical decision-support workflow during the national blood culture bottle shortage

Summary: Background: The United States Food and Drug Administration recently announced a national blood culture (BC) bottle shortage; the exact date of restoration is still being determined. Aim: Implement a workflow to mitigate the BC bottle shortage at our hospital. Methods: We created the followi...

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Main Authors: Saira Butt (Author), Amy B. Kressel (Author), Brian L. Haines (Author), Katherine Merrill (Author), Amber M. Ryan (Author), Kenneth C. Gavina (Author), Bree Weaver (Author), Michael Kays (Author), Molly Tieman (Author), Margaret Muciarelli (Author), Phillip Clapham (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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Summary:Summary: Background: The United States Food and Drug Administration recently announced a national blood culture (BC) bottle shortage; the exact date of restoration is still being determined. Aim: Implement a workflow to mitigate the BC bottle shortage at our hospital. Methods: We created the following clinical decision support workflow in electronic medical record to help mitigate BC bottle use: (a) limit to two BC in 24 hours, (b) only repeat BC if 72 hours have passed from the prior sets, (c) do not repeat BC for coagulase-negative Staphylococcus bacteremia when considered a contaminant (i.e., no implanted vascular device), (d) do not repeat BC for Streptococcus bacteremia, (e) do not repeat cultures for Gram-negative rod bacteremia unless an unknown source, immunosuppression, or clinical worsening. Findings: Post implementation, our weekly average BC bottle use decreased to 29.5%. Conclusion: Within three weeks of the BC bottle shortage announcement, we successfully deployed evidence-based BC restrictions in the electronic medical record (EMR), reducing our BC orders by 29.5%. We encourage others to consider and potentially replicate our workflow to contribute to diagnostic stewardship.
Item Description:2590-0889
10.1016/j.infpip.2024.100417