First experiences in real clinical practice treating a patient with generalised pustular psoriasis with Spesolimab

Abstract Generalised pustular psoriasis is a rare, unpredictable, and sometimes severe subtype of psoriasis whose treatment is hampered by a lack of consensus and standardised therapeutic guidelines. The recent recognition of the involvement of the innate interleukin (IL)‐1/IL‐36 pathway has allowed...

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Main Authors: Aurora Fernández‐Galván (Author), Esteban Daudén (Author), Beatriz Butron‐Bris (Author), Mireia Seguí‐Olmedilla (Author), Ana Miguélez (Author), Javier Fraga (Author), Pedro Rodríguez Jiménez (Author), Mar Llamas‐Velasco (Author)
Format: Book
Published: Wiley, 2023-06-01T00:00:00Z.
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Summary:Abstract Generalised pustular psoriasis is a rare, unpredictable, and sometimes severe subtype of psoriasis whose treatment is hampered by a lack of consensus and standardised therapeutic guidelines. The recent recognition of the involvement of the innate interleukin (IL)‐1/IL‐36 pathway has allowed the development of new biologic drugs such as Spesolimab. We present the case of a woman with persistent generalised pustular psoriasis (GGP) who, after numerous failures with several systemic and biologic therapies, was treated with Spesolimab and showed a very rapid and sustained response over time.
Item Description:2768-6566
10.1002/jvc2.149