First experiences in real clinical practice treating a patient with generalised pustular psoriasis with Spesolimab

Abstract Generalised pustular psoriasis is a rare, unpredictable, and sometimes severe subtype of psoriasis whose treatment is hampered by a lack of consensus and standardised therapeutic guidelines. The recent recognition of the involvement of the innate interleukin (IL)‐1/IL‐36 pathway has allowed...

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Main Authors: Aurora Fernández‐Galván (Author), Esteban Daudén (Author), Beatriz Butron‐Bris (Author), Mireia Seguí‐Olmedilla (Author), Ana Miguélez (Author), Javier Fraga (Author), Pedro Rodríguez Jiménez (Author), Mar Llamas‐Velasco (Author)
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Published: Wiley, 2023-06-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Aurora Fernández‐Galván  |e author 
700 1 0 |a Esteban Daudén  |e author 
700 1 0 |a Beatriz Butron‐Bris  |e author 
700 1 0 |a Mireia Seguí‐Olmedilla  |e author 
700 1 0 |a Ana Miguélez  |e author 
700 1 0 |a Javier Fraga  |e author 
700 1 0 |a Pedro Rodríguez Jiménez  |e author 
700 1 0 |a Mar Llamas‐Velasco  |e author 
245 0 0 |a First experiences in real clinical practice treating a patient with generalised pustular psoriasis with Spesolimab 
260 |b Wiley,   |c 2023-06-01T00:00:00Z. 
500 |a 2768-6566 
500 |a 10.1002/jvc2.149 
520 |a Abstract Generalised pustular psoriasis is a rare, unpredictable, and sometimes severe subtype of psoriasis whose treatment is hampered by a lack of consensus and standardised therapeutic guidelines. The recent recognition of the involvement of the innate interleukin (IL)‐1/IL‐36 pathway has allowed the development of new biologic drugs such as Spesolimab. We present the case of a woman with persistent generalised pustular psoriasis (GGP) who, after numerous failures with several systemic and biologic therapies, was treated with Spesolimab and showed a very rapid and sustained response over time. 
546 |a EN 
690 |a psoriasis 
690 |a pustular psoriasis 
690 |a Spesolimab 
690 |a Dermatology 
690 |a RL1-803 
690 |a Diseases of the genitourinary system. Urology 
690 |a RC870-923 
655 7 |a article  |2 local 
786 0 |n JEADV Clinical Practice, Vol 2, Iss 2, Pp 369-372 (2023) 
787 0 |n https://doi.org/10.1002/jvc2.149 
787 0 |n https://doaj.org/toc/2768-6566 
856 4 1 |u https://doaj.org/article/881456a38f8d4e8c992bf3b86a8c5cdb  |z Connect to this object online.