Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions

• Автори: Michelangelo Paci (Автор), Jussi T. Koivumäki (Автор), Hua Rong Lu (Автор), David J. Gallacher (Автор), Elisa Passini (Автор), Blanca Rodriguez (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Objectives: Improvements in human stem cell-derived cardiomyocyte (hSC-CM) technology have promoted their use for drug testing and disease investigations. Several in silico hSC-CM models have been proposed to augment interpretation of experimental findings through simulations. This work aims to asse...