Plumbagin Prevents Secretory Diarrhea by Inhibiting CaCC and CFTR Channel Activities

• Váldodahkkit: Bo Yu (Dahkki), Xiaojuan Zhu (Dahkki), Xinyu Yang (Dahkki), Lingling Jin (Dahkki), Jia Xu (Dahkki), Tonghui Ma (Dahkki), Hong Yang (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Secretory diarrhea, which primarily originates through intestinal pathogens and viruses, is a health burden in many regions worldwide. Enterocyte Cl− channels, as the final step in enterotoxin-induced fluid secretion, constitute an attractive class of targets for diarrhea therapy. Chloride channel i...