A potential new mechanism for pregnancy loss: considering the role of LINE-1 retrotransposons in early spontaneous miscarriage
Abstract LINE1 retrotransposons are mobile DNA elements that copy and paste themselves into new sites in the genome. To ensure their evolutionary success, heritable new LINE-1 insertions accumulate in cells that can transmit genetic information to the next generation (i.e., germ cells and embryonic...
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Main Authors: | Chao Lou (Author), John L. Goodier (Author), Rong Qiang (Author) |
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Format: | Book |
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BMC,
2020-01-01T00:00:00Z.
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