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Novel Histone Deacetylase (HDAC) Inhibitor Induces Apoptosis and Suppresses Invasion via E-Cadherin Upregulation in Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreatic cancer characterized by therapy resistance and early metastasis, resulting in a low survival rate. Histone deacetylase (HDAC) inhibitors showed potential for the treatment of hematological malignancies. In PDAC, the overex...

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Main Authors: Katja Schiedlauske (Author), Alina Deipenbrock (Author), Marc Pflieger (Author), Alexandra Hamacher (Author), Jan Hänsel (Author), Matthias U. Kassack (Author), Thomas Kurz (Author), Nicole E. Teusch (Author)
Format: Book
Published: MDPI AG, 2024-06-01T00:00:00Z.
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