Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)

• Główni autorzy: Muenyi Clarisse S (Autor), States Vanessa A (Autor), Masters Joshua H (Autor), Fan Teresa W (Autor), Helm C William (Autor), States J Christopher (Autor)
• Format: Książka
• Wydane: BMC, 2011-06-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer death in the USA. Recurrence rates are high after front-line therapy and most patients eventually die from platinum (Pt) - resistant disease. Cisplatin resist...