Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy

• Main Authors: Lan Li (Author), Jingyu Ni (Author), Min Li (Author), Jingrui Chen (Author), Lifeng Han (Author), Yan Zhu (Author), Deling Kong (Author), Jingyuan Mao (Author), Yi Wang (Author), Boli Zhang (Author), Meifeng Zhu (Author), Xiumei Gao (Author), Guanwei Fan (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Doxorubicin (DOX) is one of the most effective chemotherapy agents used in the treatment of hematological and solid tumors, however, it causes dose-related cardiotoxicity that may lead to heart failure in patients. One of the major reasons was increased reactive oxygen species (ROS) production. Gins...