Ligand-Based Drug Design of Genipin Derivatives with Cytotoxic Activity against HeLa Cell Line: A Structural and Theoretical Study

• Main Authors: Diana López-López (Author), Rodrigo Said Razo-Hernández (Author), César Millán-Pacheco (Author), Mario Alberto Leyva-Peralta (Author), Omar Aristeo Peña-Morán (Author), Jessica Nayelli Sánchez-Carranza (Author), Verónica Rodríguez-López (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cervical cancer is a malignant neoplastic disease, mainly associated to HPV infection, with high mortality rates. Among natural products, iridoids have shown different biological activities, including cytotoxic and antitumor effects, in different cancer cell types. Geniposide and its aglycone Genipi...