New MraY_AA Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole

• Главные авторы: Hongwei Wan (Автор), Raja Ben Othman (Автор), Laurent Le Corre (Автор), Mélanie Poinsot (Автор), Martin Oliver (Автор), Ana Amoroso (Автор), Bernard Joris (Автор), Thierry Touzé (Автор), Rodolphe Auger (Автор), Sandrine Calvet-Vitale (Автор), Michaël Bosco (Автор), Christine Gravier-Pelletier (Автор)
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• Опубликовано: MDPI AG, 2022-09-01T00:00:00Z.
• Предметы: article
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New inhibitors of the bacterial transferase MraY from <i>Aquifex aeolicus</i> (MraY_AA), based on the aminoribosyl uridine central core of known natural MraY inhibitors, have been designed to generate interaction of their oxadiazole linker with the key amino acids (...