Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature

Abstract Background Pyelonephritis is one of the most serious bacterial illnesses during childhood. Gram-negative organisms account for up to 90% of the cases. Gram-positive bacteria are uncommon causes of urinary tract infections, and only a few cases caused by Facklamia hominis have been reported...

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Main Authors: Samantha Pérez-Cavazos (Author), Daniela Cisneros-Saldaña (Author), Fernando Espinosa-Villaseñor (Author), José Iván Castillo-Bejarano (Author), Denisse Natalie Vaquera-Aparicio (Author), Hugo Sánchez-Alanís (Author), Abiel Mascareñas-De los Santos (Author)
Format: Book
Published: BMC, 2022-02-01T00:00:00Z.
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Summary:Abstract Background Pyelonephritis is one of the most serious bacterial illnesses during childhood. Gram-negative organisms account for up to 90% of the cases. Gram-positive bacteria are uncommon causes of urinary tract infections, and only a few cases caused by Facklamia hominis have been reported in the literature. Case presentation A five-year-old girl with tracheostomy and gastrostomy and past medical history of congenital lymphangioma presented with a two-week history of with intermittent fever, frequent urination, and vesical tenesmus. Diagnosis of pyelonephritis was made. Urine culture reported colonies with alpha-hemolysis in blood agar at 48-h of incubation and Facklamia hominis was identified by MALDI-TOF. The patient was successfully treated with gentamicin. Conclusions This is the first reported case of pyelonephritis by Facklamia hominis in a child, and the second involving infection in a pediatric patient. Although this pathogen is uncommon, current treatment of F. hominis is a challenge for physicians. This case illustrates the requirement to standardize identification and treatment of care to avoid treatment failure and antimicrobial resistance.
Item Description:10.1186/s12941-022-00497-4
1476-0711