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Pingyin rose essential oil alleviates LPS-Induced inflammation in RAW 264.7 cells via the NF-κB pathway: an integrated in vitro and network pharmacology analysis

Highlights ➢ PREO is a mixture of aromatic components, mainly monoterpenoids. ➢ PREO reduces the expression of proinflammatory cytokines and oxidative stress markers. ➢ Network pharmacological studies indicated that PREO might downregulate inflammation through the NF-κB  signaling pathway, and these...

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Main Authors: Rifat Nowshin Raka (Author), Ding Zhiqian (Author), Yuan Yue (Author), Qiao Luchang (Author), Park Suyeon (Author), Xiao Junsong (Author), Wu Hua (Author)
Format: Book
Published: BMC, 2022-10-01T00:00:00Z.
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Summary:Highlights ➢ PREO is a mixture of aromatic components, mainly monoterpenoids. ➢ PREO reduces the expression of proinflammatory cytokines and oxidative stress markers. ➢ Network pharmacological studies indicated that PREO might downregulate inflammation through the NF-κB  signaling pathway, and these results were confirmed by Western blot investigation. ➢ Molecular docking analysis revealed the potential of these compounds as possible ligands. Graphical Abstract
Item Description:10.1186/s12906-022-03748-1
2662-7671

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