What are the indications for combined use of hydroxychloroquine and lopinavir/ritonavir, and how should treatment safety monitoring be performed?

Some guidelines describe combined use of hydroxychloroquine and lopinavir/ritonavir as one of the treatment alternatives for severe COVID-19, yet this treatment is not preferable. It requires careful consideration of possible interactions with other drugs, monitoring of cardiotoxicity (including QT-...

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Bibliographic Details
Main Authors: Yu. Yu. Kiselev (Author), V. M. Tsvetov (Author), K. B. Mirzaev (Author), D. A. Sychev (Author)
Format: Book
Published: Izdatelstvo OKI, 2020-10-01T00:00:00Z.
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Summary:Some guidelines describe combined use of hydroxychloroquine and lopinavir/ritonavir as one of the treatment alternatives for severe COVID-19, yet this treatment is not preferable. It requires careful consideration of possible interactions with other drugs, monitoring of cardiotoxicity (including QT-interval measurement), and hepatotoxicity (measurement of ASAT/ ALAT).
Item Description:2588-0519
2618-8473
10.37489/2588-0519-2020-S4-47-49