Reduction of Protein Bound Methionine Sulfoxide by a Periplasmic Dimethyl Sulfoxide Reductase

• Main Authors: Lionel Tarrago (Author), Sandrine Grosse (Author), David Lemaire (Author), Laetitia Faure (Author), Mathilde Tribout (Author), Marina I. Siponen (Author), Mila Kojadinovic-Sirinelli (Author), David Pignol (Author), Pascal Arnoux (Author), Monique Sabaty (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In proteins, methionine (Met) can be oxidized into Met sulfoxide (MetO). The ubiquitous methionine sulfoxide reductases (Msr) A and B are thiol-oxidoreductases reducing MetO. Reversible Met oxidation has a wide range of consequences, from protection against oxidative stress to fine-tuned regulation...